Synthesis of 2- and 6-thienylazulenes by palladium-catalyzed direct arylation of 2- and 6-haloazulenes with thiophene derivatives.

نویسندگان

  • Taku Shoji
  • Akifumi Maruyama
  • Takanori Araki
  • Shunji Ito
  • Tetsuo Okujima
چکیده

Preparation of 2- and 6-thienylazulene derivatives was established by the palladium-catalyzed direct cross-coupling reaction of 2- and 6-haloazulenes with the corresponding thiophene derivatives in good yield. Several thienylazulene derivatives were also used in the reaction with 2-chloroazulene derivatives in the presence of the palladium-catalyst to afford the thiophene derivatives with two azulene functions in good yield.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 13 40  شماره 

صفحات  -

تاریخ انتشار 2015